Preferences of Adult Patients With Inflammatory Bowel Disease for Attributes of Clinical Trials: Evidence From a Choice-Based Conjoint Analysis.

ABSTRACT:

Background

Clinical trial recruitment is the rate-limiting step in developing new treatments. To understand inflammatory bowel disease (IBD) patient recruitment, we investigated two questions: Do changes in clinical trial attributes, like monetary compensation, influence recruitment rates, and does this influence differ across subgroups?

Methods

We answered these questions through a conjoint survey of 949 adult IBD patients.

Results

Recruitment rates are influenced by trial attributes: small but significant increases are predicted with lower placebo rates, reduced number of endoscopies, less time commitment, open label extension, and increased involvement of participant's primary GI physician. A much stronger effect was found with increased monetary compensation. Late

SUBMITTER: Wood D 

PROVIDER: S-EPMC9802344 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature