Contextualizing prescription opioid misuse and heroin use within dimensional models of drug involvement.

ABSTRACT:

Background

Prescription opioid misuse (POM) is often implicated in heroin initiation, despite evidence that POM does not predict heroin initiation any better than other drug use. Additionally, prescription misuse and illicit use behaviors tend to respectively "cluster" together. This study aimed to test a series of theory-driven factor models to explore how POM and heroin use are situated within the broader constellation of drug use that typically occurs alongside opioid (mis)use.

Methods

36,309 individuals from NESARC-III (56.31% female; mean age=45.63 [SD=17.53]) reported their lifetime (mis)use of prescription opioids, prescription stimulants, prescription sedatives, heroin, cannabis, cocaine/crack, illicit stimulants (e.g., methamphetamine), club drugs, hallucinogens, an

SUBMITTER: Dash GF 

PROVIDER: S-EPMC9802645 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature