Influence of metformin intake on serum vitamin B12 levels in patients with type 2 diabetes mellitus.

ABSTRACT:

Objective

To describe the prevalence of vitamin B12 deficiency among Jordanian patients with type 2 diabetes mellitus treated with metformin and to compare the findings with those who did not receive metformin.

Design and method

Total 155 patients with type 2 diabetes mellitus, aged between 48 and 82 years were enrolled in the current study. They were divided into two groups; the first (n = 120) was treated with metformin while the second (n = 35) was not. Patients' demographics (age, gender, duration of type 2 diabetes mellitus, smoking status), medication parameters (daily dosage and duration of metformin therapy), and biochemical parameters (hemoglobin level, mean corpuscular volume (MCV), serum vitamin B12, and folate level) were recorded. Definite deficiency was defined

SUBMITTER: Al-Fawaeir S 

PROVIDER: S-EPMC9803116 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature