Gestational diabetes in women with obesity; an analysis of clinical history and simple clinical/anthropometric measures

ABSTRACT:

Aim

We assessed clinical risk factors, anthropometric measures of adiposity and weight gain to determine associations with development of GDM in a cohort of pregnant women with obesity.

Methods

This was a secondary analysis of the UPBEAT trial of a complex lifestyle intervention in pregnant women with obesity (ISRCTN89971375). Clinical risk factors, and measures of adiposity and weight were assessed in the early 2nd trimester (mean 17 +0 weeks), and adiposity and weight repeated in the early 3rd trimester (mean 27 +5 weeks’).

Results

Of the 1117 women (median BMI 35.0 kg/m2) with complete data, 25.8% (n = 304) developed GDM (IADPSG criteria, OGTT 24-28weeks). Using multivariable analysis, early clinical risk factors associated with later development of GDM includ

SUBMITTER: White S 

PROVIDER: S-EPMC9803279 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature