Association between polymorphisms in miRNAs and ischemic stroke: A meta-analysis.

ABSTRACT:

Background

Atherosclerosis remains a predominant cause of ischemic stroke (IS). Four miRNA polymorphisms associated with arteriosclerosis mechanism were meta-analyzed to explore whether they had predictive significance for IS.

Methods

PubMed, Excerpta Medica database, Web of Science, Cochrane Library, Scopus, China National Knowledge Infrastructure, and China Wanfang Database were searched for relevant case-control studies published before September 2022. Two researchers independently reviewed the studies and extracted the data. Data synthesis was carried out on eligible studies. Meta-analysis, subgroup analysis, sensitivity analysis, and publication bias analysis were performed using Stata software 16.0.

Results

Twenty-two studies were included, comprising 8879 cases

SUBMITTER: Jing Y 

PROVIDER: S-EPMC9803434 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature