Simultaneous ¹⁸F-FDG PET/MR metabolic and structural changes in visual snow syndrome and diagnostic use.

ABSTRACT:

Purpose

Visual snow syndrome (VSS) is a recently recognized chronic neurologic condition characterized by the constant perceiving of tiny flickering dots throughout the entire visual field. Metabolic overactivity and grey matter volume increase in the lingual gyrus has been reported. We investigated this by ¹⁸F-FDG PET/MR in comparison to healthy controls. Aside from voxel-based characterization, the classification accuracy of volume-of-interest (VOI)-based multimodal assessment was evaluated, also in comparison with visual analysis.

Methods

Simultaneous ¹⁸F-FDG PET and MR imaging was performed in 7 patients with VSS (24.6 ± 5.7 years; 5 M/2F) and 15 age-matched healthy controls (CON) (28.0 ± 5.3 years; 8 M/7F). SPM12 and voxel-based morphometric analys

SUBMITTER: Van Laere K 

PROVIDER: S-EPMC9803799 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature