Frailty is a stronger predictor of death in younger intensive care patients than in older patients: a prospective observational study.

ABSTRACT:

Background

While frailty is a known predictor of adverse outcomes in older patients, its effect in younger populations is unknown. This prospective observational study was conducted in a tertiary-level mixed ICU to assess the impact of frailty on long-term survival in intensive care patients of different ages.

Methods

Data on premorbid frailty (Clinical Frailty Score; CFS), severity of illness (the Simplified Acute Physiology Score, third version; SAPS3), limitations of care and outcome were collected in 817 adult ICU patients. Hazard ratios (HR) for death within 180 days after ICU admission were calculated. Unadjusted and adjusted analyses were used to evaluate the association of frailty with outcome in different age groups.

Results

Patients were classified into pred

SUBMITTER: De Geer L 

PROVIDER: S-EPMC9803889 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature