Ultra-sensitive terahertz metamaterials biosensor based on luxuriant gaps structure.

ABSTRACT: Fast, simple, and label-free detections and distinctions are desirable in cell biology analysis and diagnosis. Here, a biosensor based on terahertz metamaterial has luxuriant gaps, which can excite dipole resonance is designed. Filling the gaps with various analytes can change the biosensor's capacitance resulting in electromagnetic properties changing. The idea is verified by simulations and experiments. The theoretical sensitivity of the biosensor approaches 290 GHz/RIU, and the experimental concentration sensitivity of the biosensor is ≥ 275 kHz mL/cell. Candida Albicans, Escherichia Coli, and Shigella Dysenteriae were selected as analytes, and the measurement frequency shift is 270 GHz, 290 GHz, and 310 GHz, respectively, which indicates that the biosensor can detect and distinguish th

SUBMITTER: Chen K 

PROVIDER: S-EPMC9804134 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature