Episodic memory network connectivity in temporal lobe epilepsy.

ABSTRACT:

Objective

Temporal lobe epilepsy (TLE) affects brain networks and is associated with impairment of episodic memory. Temporal and extratemporal reorganization of memory functions is described in functional magnetic resonance imaging (fMRI) studies. Functional reorganizations have been shown at the local activation level, but network-level alterations have been underinvestigated. We aim to investigate the functional anatomy of memory networks using memory fMRI and determine how this relates to memory function in TLE.

Methods

Ninety patients with unilateral TLE (43 left) and 29 controls performed a memory-encoding fMRI paradigm of faces and words with subsequent out-of-scanner recognition test. Subsequent memory event-related contrasts of words and faces remembered were generat

SUBMITTER: Fleury M 

PROVIDER: S-EPMC9804196 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature