Parents' experiences with large-scale sequencing for genetic predisposition in pediatric renal cancer: A qualitative study.

ABSTRACT:

Objective

In pediatric oncology, large-scale genetic sequencing contributes to the identification of cancer predisposition, which can facilitate surveillance and family counseling. Our qualitative study explores families' motives, knowledge, and views regarding germline genetic sequencing to improve future counseling and support.

Methods

Semi-structured interviews were conducted with parents of children with renal tumors participating in a national center, germline sequencing study. An inductive thematic analysis approach was used. Twenty nine parents participated, 17 mothers and 12 fathers. The median age of the affected children was 4 years.

Results

Parents were generally positive about sequencing and reported a combination of individual and altruistic motives to pa

SUBMITTER: Bon SBB 

PROVIDER: S-EPMC9804506 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature