Liver transplantation for NAFLD cirrhosis: Age and recent coronary angioplasty are major determinants of survival.

ABSTRACT:

Background and aims

Liver transplantation (LT) is the treatment of end-stage non-alcoholic liver disease (NAFLD), that is decompensated cirrhosis and/or complicated by hepatocellular carcinoma (HCC). Few data on long-term outcome are available. The aim of this study was to evaluate overall patient and graft survivals and associated predictive factors.

Method

This retrospective multicentre study included adult transplant patients for NAFLD cirrhosis between 2000 and 2019 in participating French-speaking centres.

Results

A total of 361 patients (69.8% of male) were included in 20 centres. The median age at LT was 62.3 years [57.4-65.9] and the median MELD score was 13.9 [9.1-21.3]; 51.8% of patients had HCC on liver explant. Between 2004 and 2018, the number of LT for N

SUBMITTER: Villeret F 

PROVIDER: S-EPMC9804523 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature