Extrahepatic autoimmune diseases in autoimmune hepatitis: Effect on mortality.

ABSTRACT:

Background and aims

Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease associated with an increased prevalence of extrahepatic autoimmune diseases and an increased mortality compared with the general population. The contribution of extrahepatic autoimmune diseases to the increased mortality has not been clarified. Our aim was to determine the effect of extrahepatic autoimmune diseases on mortality in AIH patients.

Methods

This nationwide register-based cohort study included all Danish patients diagnosed with AIH between 1995 and 2019. We examined the presence of extrahepatic autoimmune diseases and compared the mortality between AIH patients with and without extrahepatic autoimmune diseases. We adjusted our analysis for age, sex, calendar year of AIH diagnosi

SUBMITTER: Birn-Rydder R 

PROVIDER: S-EPMC9804558 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature