Simplified and accessible [¹⁸ F]F-AraG synthesis procedure for preclinical PET.

ABSTRACT: The PET tracer [¹⁸ F]F-AraG, an arabinosyl guanine analog, has shown promise for visualizing activated T cells in multiple diseases. Herein, a practitioner's protocol is described, in which the PET tracer is prepared using minimal equipment and manual actions, making it widely accessible for preclinical applications.

SUBMITTER: Hognasbacka AA 

PROVIDER: S-EPMC9804570 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature