External validation of the Predicting Asthma Risk in Children tool in a clinical cohort.

ABSTRACT:

Introduction

The Predicting Asthma Risk in Children (PARC) tool uses questionnaire-based respiratory symptoms collected from preschool children to predict asthma risk 5 years later. The tool was developed and validated in population cohorts but not validated using a clinical cohort. We aimed to externally validate the PARC tool in a pediatric pulmonology clinic setting.

Methods

The Swiss Paediatric Airway Cohort (SPAC) is a prospective cohort of children seen in pediatric pulmonology clinics across Switzerland. We included children aged 1-6 years with cough or wheeze at baseline who completed the 2-year follow-up questionnaire. The outcome was defined as current wheeze plus use of asthma medication. We assessed performance using: sensitivity, specificity, negative predictive

SUBMITTER: Berger DO 

PROVIDER: S-EPMC9804745 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature