Outcome and long-term treatment protocol for topical tacrolimus in oral lichen planus.

ABSTRACT:

Background and objective

Topical tacrolimus has been shown to be beneficial in the treatment of oral lichen planus (OLP). However, long-term effects and its optimal application protocol with gradual reduction have not been studied. Accordingly, we analysed the clinical response of OLP to tacrolimus in our daily clinical practice with a focus on the optimal long-term therapeutic scheme.

Methods

Retrospective analysis of all consecutive patients diagnosed with OLP and treated with topical tacrolimus (0.03% oral rinse) in a clinical setting between 2015 and 2020. The objective clinical response was measured by a 4-point scale (complete remission, major remission, partial remission and no response), and subjective impairment by a 3-point scale (severe, moderate and none).

Res

SUBMITTER: Utz S 

PROVIDER: S-EPMC9804806 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature