Dried blood spots are a valid alternative to venipuncture for COVID-19 antibody testing.

ABSTRACT:

Background

Serologic analysis is an important tool towards assessing the humoral response to COVID-19 infection and vaccination. Numerous serologic tests and platforms are currently available to support this line of testing. Two broad antibody testing categories are point-of-care lateral flow immunoassays and semi-quantitative immunoassays performed in clinical laboratories, which typically require blood collected from a finger-stick and a standard venipuncture blood draw, respectively. This study evaluated the use of dried blood spot (DBS) collections as a sample source for COVID-19 antibody testing using an automated clinical laboratory test system.

Methods

Two hundred and ninety-four participants in the BLAST COVID-19 seroprevalence study (NCT04349202) were recruited at t

SUBMITTER: Sims MD 

PROVIDER: S-EPMC9804961 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature