Outcomes in patients undergoing periprocedural interruption of warfarin or direct oral anticoagulants.

ABSTRACT:

Background

Differences in clinical outcomes following a temporary interruption of warfarin or a direct oral anticoagulant (DOAC) for a surgical procedure are not well described. Differences in patient characteristics from practice-based cohorts have not typically been accounted for in prior analyses.

Aim

To describe risk-adjusted differences in postoperative outcomes following an interruption of warfarin vs DOACs.

Methods

Patients receiving care at six anticoagulation clinics participating in the Michigan Anticoagulation Quality Improvement Initiative were included if they had at least one oral anticoagulant interruption for a procedure. Inverse probability of treatment weighting (IPTW) was used to balance baseline differences between the warfarin cohort and DOAC coho

SUBMITTER: Lee J 

PROVIDER: S-EPMC9804988 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature