Hospital-diagnosed sleep disorders and incident dementia: a nationwide observational cohort study.

ABSTRACT:

Background and purpose

Several smaller, community-based studies have suggested a link between sleep disorders and dementia with a focus on sleep as a modifiable risk factor for dementia. Studies on neurodegenerative diseases are prone to reverse causation, and few studies have examined the association with long follow-up time. Our aim was to explore the possible association between sleep disorders and late-onset dementia in an entire population.

Methods

In a nationwide cohort with 40-year follow-up, associations between hospital-based sleep disorder diagnoses and late-onset dementia were assessed. Incidence rate ratios (IRR) were calculated using Poisson regression.

Results

The cohort consisted of 1,491,276 people. Those with any sleep disorder had a 17% higher risk o

SUBMITTER: Damsgaard L 

PROVIDER: S-EPMC9805192 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature