Advanced characterization of magnetization dynamics in iron oxide magnetic nanoparticle tracers.

ABSTRACT: Characterization of the magnetization dynamics of single-domain magnetic nanoparticles (MNPs) is important for magnetic particle imaging (MPI), magnetic resonance imaging (MRI), and emerging medical diagnostic/therapeutic technologies. Depending on particle size and temperature, nanoparticle magnetization relaxation time constants span from nanoseconds to seconds. In solution, relaxation occurs via coupled Brownian and Néel relaxation mechanisms. Even though their coexistence complicates analysis, the presence of two timescales presents opportunities for more direct control of magnetization behavior if the two processes can be understood, isolated, and tuned. Using high frequency coils and sample temperature tunability, we demonstrate unambiguous determination of the specific relaxation pr

SUBMITTER: Bui TQ 

PROVIDER: S-EPMC9805320 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature