Correlation Analysis of Gene and Radiomic Features in Colorectal Cancer Liver Metastases.

ABSTRACT: Colorectal cancer liver metastasis (CRLM) was one of the cancers with high mortality. Clinically, the target point was determined by invasive detection, which increased the suffering of patients and the cost of treatment. If the target point was found through the relationship between early radiomic information and genetic information, it was expected to assist doctors in diagnosing disease, formulating treatment plans, and reducing the pain and burden of patients. In this study, gene coexpression analysis and hub gene mining were first performed on the gene data; secondly, quantitative radiomic features were extracted from CT-enhanced radiomic data to obtain features highly correlated with CRLM; and finally, we analyzed the relationship between gene features and radiomic feature correlatio

SUBMITTER: Wang X 

PROVIDER: S-EPMC9805395 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature