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STRIKE-GOLDD 4.0: user-friendly, efficient analysis of structural identifiability and observability.


ABSTRACT:

Motivation

STRIKE-GOLDD is a toolbox that analyses the structural identifiability and observability of possibly non-linear, non-rational ODE models that may have known and unknown inputs. Its broad applicability comes at the expense of a lower computational efficiency than other tools.

Results

STRIKE-GOLDD 4.0 includes a new algorithm, ProbObsTest, specifically designed for the analysis of rational models. ProbObsTest is significantly faster than the previously available FISPO algorithm when applied to computationally expensive models. Providing both algorithms in the same toolbox allows combining generality and computational efficiency. STRIKE-GOLDD 4.0 is implemented as a Matlab toolbox with a user-friendly graphical interface.

Availability and implementation

STRIKE-GOLDD 4.0 is a free and open-source tool available under a GPLv3 license. It can be downloaded from GitHub at https://github.com/afvillaverde/strike-goldd.

Supplementary information

Supplementary data are available at Bioinformatics online.

SUBMITTER: Diaz-Seoane S 

PROVIDER: S-EPMC9805590 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature

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Publications

STRIKE-GOLDD 4.0: user-friendly, efficient analysis of structural identifiability and observability.

Díaz-Seoane Sandra S   Rey Barreiro Xabier X   Villaverde Alejandro F AF  

Bioinformatics (Oxford, England) 20230101 1


<h4>Motivation</h4>STRIKE-GOLDD is a toolbox that analyses the structural identifiability and observability of possibly non-linear, non-rational ODE models that may have known and unknown inputs. Its broad applicability comes at the expense of a lower computational efficiency than other tools.<h4>Results</h4>STRIKE-GOLDD 4.0 includes a new algorithm, ProbObsTest, specifically designed for the analysis of rational models. ProbObsTest is significantly faster than the previously available FISPO alg  ...[more]

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