Hospitalised COVID-19 outcomes are predicted by hypoxaemia and pneumonia phenotype irrespective of the timing of their emergence.

ABSTRACT: Despite the known clinical importance of hypoxemia and pneumonia, there is a paucity of evidence for these variables with respect to risk of mortality and short-term outcomes among those hospitalised with COVID-19.

Objective

Describe the prevalence and clinical course of patients hospitalised with COVID-19 based on oxygenation and pneumonia status at presentation and determine the incidence of emergent hypoxaemia or radiographic pneumonia during admission.

Methods

A retrospective study was conducted using a Canadian regional registry. Patients were stratified according to hypoxaemia/pneumonia phenotype and prevalence. Clinical parameters were compared between phenotypes using χ² and one-way Analysis of variance (ANOVA). Cox analysis estimated adjusted Hazard Ratios

SUBMITTER: Salter B 

PROVIDER: S-EPMC9805826 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature