Association between serum uric acid/HDL-cholesterol ratio and chronic kidney disease: a cross-sectional study based on a health check-up population.

ABSTRACT:

Objective

Evidence suggests that both serum uric acid (SUA) and high-density lipoprotein cholesterol (HDL-C) are risk factors for chronic kidney disease (CKD). The SUA-to-HDL-C ratio (UHR) has recently attracted attention as a new biomarker to evaluate the role between inflammatory and anti-inflammatory substances. Thus, we explored the association between UHR and CKD in a large Chinese population.

Design

A cross-sectional study.

Setting

Annual health check-up population in Nanjing.

Participants

19 458 individuals who underwent an annual health check-up in 2019 were included in our study.

Main outcome measure

CKD was diagnosed according to an estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m².

Results

Correlation analysis sh

SUBMITTER: Cheng Y 

PROVIDER: S-EPMC9806076 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature