Alterations in Social Brain Network Topology at Rest in Children With Autism Spectrum Disorder.

ABSTRACT:

Objective

Underconnectivity in the resting brain is not consistent in autism spectrum disorder (ASD). However, it is known that the functional connectivity of the default mode network is mainly decreased in childhood ASD. This study investigated the brain network topology as the changes in the connection strength and network efficiency in childhood ASD, including the early developmental stages.

Methods

In this study, 31 ASD children aged 2-11 years were compared with 31 age and sex-matched children showing typical development. We explored the functional connectivity based on graph filtration by assessing the single linkage distance and global and nodal efficiencies using resting-state functional magnetic resonance imaging. The relationship between functional connectivity and

SUBMITTER: Yoon N 

PROVIDER: S-EPMC9806512 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature