Topography of Prostate Cancer Recurrence: A Single-centre Analysis of Salvage Radical Prostatectomy Specimens and Implications for Focal Salvage Treatments

ABSTRACT: Take Home Message Salvage radical prostatectomy is a therapeutic option still associated with a high postoperative morbidity rate. Salvage focal treatments could be a viable therapeutic alternative, but there are few studies on the topography of prostate cancer recurrence and a lack of theoretical confirmation of the viability of such an approach.

Background

Most prostate cancer (PCa) recurrences after nonsurgical first-line treatment are managed with androgen deprivation therapy (ADT). When local treatment is indicated, salvage focal treatment (FT) may achieve outcomes similar to those after salvage radical prostatectomy (sRP), with lower morbidity. However, descriptions of the topography of PCa recurrence are scarce.

Objective

To describe the characteristics and topogra

SUBMITTER: Marra G 

PROVIDER: S-EPMC9806711 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature