Association of indoor dust microbiota with cognitive function and behavior in preschool-aged children.

ABSTRACT:

Background

Childhood cognitive development depends on neuroimmune interactions. Immunomodulation by early-life microbial exposure may influence neuropsychological function. In this study, we investigate the association between residential indoor microbiota and cognition and behavior among preschoolers.

Results

Indoor-settled dust bacterial and fungal characteristics were assessed using 16S and ITS amplicon sequencing (microbial diversity) and qPCR measurements (microbial loads). Child behavior was assessed using four scales: peer relationship, emotional, conduct, and hyperactivity was assessed by the Strengths and Difficulties Questionnaire (SDQ). Cognitive function was assessed using four tasks of the Cambridge Neuropsychological Test Automated Battery (CANTAB) software. Th

SUBMITTER: Dockx Y 

PROVIDER: S-EPMC9806900 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature