Determinants of long COVID among adults hospitalized for SARS-CoV-2 infection: A prospective cohort study.

ABSTRACT:

Rationale

Factors associated with long-term sequelae emerging after the acute phase of COVID-19 (so called "long COVID") are unclear. Here, we aimed to identify risk factors for the development of COVID-19 sequelae in a prospective cohort of subjects hospitalized for SARS-CoV-2 infection and followed up one year after discharge.

Methods

A total of 324 subjects underwent a comprehensive and multidisciplinary evaluation one year after hospital discharge for COVID-19. A subgroup of 247/324 who consented to donate a blood sample were tested for a panel of circulating cytokines.

Results

In 122 patients (37.8%) there was evidence of at least one persisting physical symptom. After correcting for comorbidities and COVID-19 severity, the risk of developing long COVID was lower

SUBMITTER: Bellan M 

PROVIDER: S-EPMC9807078 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature