Screening for phthalates biomarkers and its potential role in infertility outcomes in Jordan.

ABSTRACT:

Background

Phthalates are endocrine disrupting chemicals that are used in plastic and personal care products. Phthalate exposure has been linked to reproductive and fertility outcomes.

Objectives

This study aimed to assess the phthalate exposures using both urinary level of two DEHP metabolites in females and questionnaires. It also aimed to investigate the association between phthalate levels and reproductive and fertility outcomes.

Methods

325 females with and without fertility problems at gynaecology clinics filled out a questionnaire and provided a urine sample. Urine samples were analyzed for two DEHP metabolites: MEHHP, mono (2-ethyl-5-hydroxyhexyl) phthalate; MEOHP, mono (2-ethyl-5-oxohexyl) phthalate, using an HPLC/MS/MS analytical method.

Results

We ob

SUBMITTER: Abdo N 

PROVIDER: S-EPMC9807094 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature