Effect of BCG on Respiratory Complications Caused by COVID-19: A Scoping Review.

ABSTRACT:

Introduction

Bacillus Calmette-Guérin (BCG) has been shown to have protective effects against respiratory viruses. We conducted a scoping review of the literature to clarify the available evidence regarding the effect of BCG therapy in preventing respiratory complications of coronavirus disease 2019 (COVID-19).

Methods

We searched PubMed, Embase, CENTRAL, Scopus, and Web of Science for related studies up to October 2022.

Results

In total, 35 publications and trials were included. One animal study, two observational studies, and six finalized trials measured the effect of BCG administration on respiratory complications of COVID-19. The remaining publications included eight unfinished trials, 12 ecological studies, and six observational studies that did not directly mea

SUBMITTER: da Costa CG 

PROVIDER: S-EPMC9807169 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature