Variability in Resting-State Functional Magnetic Resonance Imaging: The Effect of Body Mass, Blood Pressure, Hematocrit, and Glycated Hemoglobin on Hemodynamic and Neuronal Parameters.

ABSTRACT: Introduction: Replicability has become an increasing focus within the scientific communities with the ongoing "replication crisis." One area that appears to struggle with unreliable results is resting-state functional magnetic resonance imaging (rs-fMRI). Therefore, the current study aimed at improving the knowledge of endogenous factors that contribute to inter-individual variability. Methods: Arterial blood pressure (BP), body mass, hematocrit, and glycated hemoglobin were investigated as potential sources of between-subject variability in rs-fMRI, in healthy individuals. Whether changes in resting-state networks (rs-networks) could be attributed to variability in the blood-oxygen-level-dependent (BOLD)-signal, changes in neuronal activity, or both was of spec

SUBMITTER: Sjuls GS 

PROVIDER: S-EPMC9807254 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature