Long-term oncological outcomes after local excision of T1 rectal cancer.

ABSTRACT:

Background

A growing proportion of patients with early rectal cancer is treated by local excision only. The aim of this study was to evaluate long-term oncological outcomes and the impact of local recurrence on overall survival for surgical local excision in pT1 rectal cancer.

Methods

Patients who only underwent local excision for pT1 rectal cancer between 1997 and 2014 in two Dutch tertiary referral hospitals were included in this retrospective cohort study. The primary outcome was the local recurrence rate. Secondary outcomes were distant recurrence, overall survival and the impact of local recurrence on overall survival.

Results

A total of 150 patients (mean age 68.5 ± 10.7 years, 57.3% males) were included in the study. Median length of follow-up was 58.9 months (

SUBMITTER: Leijtens JWA 

PROVIDER: S-EPMC9807482 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature