Required distal mesorectal resection margin in partial mesorectal excision: a systematic review on distal mesorectal spread.

ABSTRACT:

Background

The required distal margin in partial mesorectal excision (PME) is controversial. The aim of this systematic review was to determine incidence and distance of distal mesorectal spread (DMS).

Methods

A systematic search was performed using PubMed, Embase and Google Scholar databases. Articles eligible for inclusion were studies reporting on the presence of distal mesorectal spread in patients with rectal cancer who underwent radical resection.

Results

Out of 2493 articles, 22 studies with a total of 1921 patients were included, of whom 340 underwent long-course neoadjuvant chemoradiotherapy (CRT). DMS was reported in 207 of 1921 (10.8%) specimens (1.2% in CRT group and 12.8% in non-CRT group), with specified distance of DMS relative to the tumor in 84 (40.6%

SUBMITTER: Gruter AAJ 

PROVIDER: S-EPMC9807492 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature