Association between weight change and risk of metabolic abnormalities in non-overweight/obese and overweight/obese population: A retrospective cohort study among Chinese adults.

ABSTRACT:

Objectives

To explore the effects of weight change on the risk of metabolic abnormalities in the Chinese population.

Methods

A total of 1895 metabolically healthy adults aged 21-78 years completed anthropometric and biological measurements at baseline (2012) and at an eight year follow-up (2020). Based on absolute weight change and relative weight change, the participants were split into five classes. A Cox proportional hazards regression model was used to estimate the relative risk (RR) and 95% confidence intervals (95% CI) for the risk of metabolic abnormalities using stable weight as the reference group. Stratified analysis was used to explore this relationship in participants with different baseline body mass index (BMI) levels.

Results

During the follow-up period

SUBMITTER: Dai Y 

PROVIDER: S-EPMC9808089 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature