Systematic review and meta-analysis of neonatal outcomes of COVID-19 vaccination in pregnancy.

ABSTRACT:

Background

The safety of coronavirus disease 2019 (COVID-19) vaccines during pregnancy is a particular concern. Here, we addressed the neonatal outcomes after maternal vaccination of COVID-19 during pregnancy.

Methods

We systematically searched PubMed, EMBASE, and the WHO COVID-19 Database for studies on neonatal outcomes after maternal COVID-19 vaccination from inception to 3 July 2022. Main neonatal outcomes were related to preterm, small for gestation (SGA), NICU admission, low Apgar score at 5 min (<7), and additional neonatal outcomes such as gestation <34 weeks, low birth weight and some neonatal morbidity were all also analyzed.

Results

A total of 15 studies were included. We found that maternal vaccination during pregnancy was related to the reduction rates of

SUBMITTER: Zhang D 

PROVIDER: S-EPMC9808682 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature