Clinical Profiles of Asians with NAFLD: A Systematic Review and Meta-Analysis.

ABSTRACT:

Introduction

NAFLD is increasingly prevalent in Asia, where people suffer more metabolic comorbidities at a lower body mass index (BMI), suggesting potential differences in their clinical profile. Therefore, we attempted to characterize the clinical profile of Asians with NAFLD via a meta-analytic approach.

Methods

We searched PubMed, EMBASE, and Cochrane databases from January 1, 2000, to January 17, 2019. Two authors independently reviewed and selected 104 articles (2,247,754 persons) that identified NAFLD in Asians and reported relevant data, especially BMI and ALT, and excluded individuals with other liver disease and excessive alcohol consumption. Individual patient-level data were obtained from seven cohorts in Asia to complement meta-analyzed data.

Results

Over

SUBMITTER: Kam LY 

PROVIDER: S-EPMC9808705 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature