Trends in carbapenem resistance in Pre-COVID and COVID times in a tertiary care hospital in North India.

ABSTRACT:

Background

Carbapenem resistance is endemic in the Indian sub-continent. In this study, carbapenem resistance rates and the prevalence of different carbapenemases were determined in Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa during two periods; Pre-COVID (August to October 2019) and COVID (January to February 2021) in a north-Indian tertiary care hospital.

Methods

Details of patient demographics and clinical condition was collated from the Hospital Information System and detection of carbapenemases NDM, OXA-48, VIM, IMP and KPC was done by Polymerase chain reaction (PCR) in 152 and 138 non-consecutive carbapenem resistant isolates during the two study periods respectively. Conjugation assay and sequencing of NDM and OXA-48 gene w

SUBMITTER: Chatterjee N 

PROVIDER: S-EPMC9808733 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature