Transcriptomic analysis of Listeria monocytogenes biofilm formation at different times.

ABSTRACT: Biofilm (BF) formation is a considerable obstacle to the effective control of Listeria monocytogenes (LM). In this study, we used transcriptomics to analyze LM BF and planktonic bacteria at different stages of BF formation and growth to compare differential gene expression between the 2. We identified 1588, 1517, and 1462 differentially expressed genes (DEGs) when early formation BF and planktonic bacteria were compared at 12, 24, and 48 h, respectively. Among these, 1123 DEGs were shared across the 3 data pool. Gene Ontology functional enrichment and Kyoto Encyclopedia of Genes and Genomes pathway analyses demonstrated significant changes associated with the phosphotransferase system, the microbial metabolism in diverse environments, the flagella assembly, the bacterial chemotaxis,

SUBMITTER: Gou H 

PROVIDER: S-EPMC9808878 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature