Prognostic significance of inflammatory and nutritional markers in perioperative period for patients with advanced gastric cancer.

ABSTRACT:

Background

It has been reported that inflammatory and nutritional markers are related to prognosis in numerous malignancies. The present study analyzed the significance of these markers' alterations during neoadjuvant chemotherapy in the long-term outcomes in patients with advanced gastric cancer.

Methods

A retrospective review was performed of 437 advanced gastric cancer patients who underwent a neoadjuvant chemotherapy (NACT) regimen followed by surgical treatment. Inflammatory and nutritional markers measured from the blood samples collected from the patients before the first neoadjuvant chemotherapy and after the last neoadjuvant chemotherapy were used for analysis. Statistical analysis, including Mann-Whitney U or chi-square tests, the Kaplan-Meier method and Cox multiv

SUBMITTER: Zhang R 

PROVIDER: S-EPMC9808945 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature