Quantifying the daily intake of water from morning and spot urine samples; retrospective analysis of a clinical trial in volunteers.

ABSTRACT:

Background

The hydration status can be indicated by biomarkers in the urine. However, the sensitivity and specificity of single measurements of biomarkers in morning urine and spot urine samples to quantify previous and current daily water ingestion is unclear.

Methods

The water content of food and liquid consumed by 20 volunteers (mean age 42 years) was calculated daily for two weeks. The volunteers increased their consumption of water by approximately 30% during the second week. They measured their excreted urine volume and sampled the morning urine and 24-h collections of urine for analysis of osmolality and creatinine during the first four days of both weeks (N = 157). The same biomarkers of hydration were measured in spot samples taken at every voiding on the other days

SUBMITTER: Hahn RG 

PROVIDER: S-EPMC9809043 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature