Temporal, biomechanical evaluation of a novel, transcatheter polymeric aortic valve in ovine aortic banding model.

ABSTRACT:

Objectives

The aim of the study is to evaluate the functionality, durability, and temporal biocompatibility of a novel, balloon-expandable polymeric transcatheter heart valve (ATHV) system (InFlow, CardValve Consortium, Poland). Along with expanding TAVI indications, the demand for new transcatheter valves is increasing.

Methods

A surgical ascending aortic banding model was created in 20 sheep. Two weeks later, 16 sheep were implanted with ATHV systems (15-16F). Three animals were euthanized after a 30-day follow-up, four animals after a 90-day follow-up, and six animals after a 180-day follow-up. A follow-up transthoracic echocardiography (TTE) was performed.

Results

There was one procedure-related (6,25%) and two model-related deaths (12,5%; banding site calcificati

SUBMITTER: Kachel M 

PROVIDER: S-EPMC9810075 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature