Adherence to the Mediterranean diet and grade group progression in localized prostate cancer: An active surveillance cohort.

ABSTRACT:

Background

The Mediterranean diet (MD) may be beneficial for men with localized prostate cancer (PCa) on active surveillance (AS) because of its anti-inflammatory, antilipidemic, and chemopreventive properties. This study prospectively investigated adherence to the MD with Gleason score progression and explored associations by diabetes status, statin use, and other factors.

Methods

Men with newly diagnosed PCa on an AS protocol (n = 410) completed a baseline food frequency questionnaire, and the MD score was calculated across 9 energy-adjusted food groups. Cox proportional hazards models were fit to evaluate multivariable-adjusted associations of the MD score with progression-free survival; progression was defined as an increase in the Gleason grade group (GG) score over a b

SUBMITTER: Gregg JR 

PROVIDER: S-EPMC9810094 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature