Long-term cardiology outcomes in children after early treatment for Chagas disease, an observational study.

ABSTRACT:

Background

Parasite persistence after acute infection with Trypanosoma cruzi is an important factor in the development of Chagas disease (CD) cardiomyopathy. Few studies have investigated the clinical effectiveness of CD treatment through the evaluation of cardiological events by long term follow-up of treated children. Cardiological evaluation in children is challenging since features that would be diagnosed as abnormal in an adult's ECG may be normal, age-related findings in a pediatric ECG trace. The objective was to evaluate cardiac involvement in patients with Chagas disease with a minimum follow-up of 6 years post-treatment.

Methodology

A descriptive study of a cohort of pediatric patients with CD treated with benznidazole (Bz) or nifurtimox (Nf) was conducted. Childre

SUBMITTER: Gonzalez NL 

PROVIDER: S-EPMC9810160 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature