Ontology highlight
ABSTRACT:
SUBMITTER: Coughlan G
PROVIDER: S-EPMC9810179 | biostudies-literature | 2023
REPOSITORIES: biostudies-literature
Coughlan Gillian G Plumb William W Zhukovsky Peter P Aung Min Hane MH Hornberger Michael M
PloS one 20230103 1
Path integration changes may precede a clinical presentation of Alzheimer's disease by several years. Studies to date have focused on how spatial cell changes affect path integration in preclinical AD. However, vestibular input is also critical for intact path integration. Here, we developed the vestibular rotation task that requires individuals to manually point an iPad device in the direction of their starting point following rotational movement, without any visual cues. Vestibular features we ...[more]