Periconceptional folic acid supplementation and child asthma: a Right From the Start follow-up study.

ABSTRACT:

Objective

High maternal folic acid exposure has been studied as a risk factor for child asthma with inconclusive results. Folic acid supplementation that begins before pregnancy may propagate high exposures during pregnancy, particularly in regions with fortified food supplies. We investigated whether folic acid supplementation initiated periconceptionally is associated with childhood asthma in a US cohort.

Materials and methods

We re-contacted mother-child dyads previously enrolled in a prospective pregnancy cohort and included children age 4 to 8 years at follow-up (n = 540). Using first trimester interviews, we assessed whether initial folic acid-containing supplement (FACS) use occurred near/before estimated conception ("periconceptional") or after (during the "fi

SUBMITTER: Adgent MA 

PROVIDER: S-EPMC9810277 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature