Drug-Coated Balloons for Acute Myocardial Infarction: A Metaanalysis of Randomized Clinical Trials.

ABSTRACT:

Background

The role of a drug-coated balloon (DCB) in the treatment of acute myocardial infarction (AMI) is not well established.

Methods

Five databases were searched for randomized controlled trials that compared DCB with stents in the treatment of AMI from their inception to 30 July 2021. The primary clinical endpoint was major adverse cardiac events (MACEs). Summary estimations were conducted using fixed-effects analysis complemented by several subgroups. The protocol was registered with PROSPERO (https://clinicaltrials.gov/ct2/show/CRD42021272886).

Results

A total of 4 randomized controlled trials with 485 patients were included. On routine clinical follow-up, DCB was associated with no difference in the incidence of MACEs compared with control (risk ratio [RR] 0.

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC9810407 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature