Sex differences in the progression of cerebral microbleeds in patients with concomitant cerebral small vessel disease.

ABSTRACT:

Background and purpose

Sex differences in cerebral microbleeds (CMBs) are not well-known. We aimed to assess the impact of sex on the progression of CMBs.

Methods

The CHALLENGE (Comparison Study of Cilostazol and Aspirin on Changes in Volume of Cerebral Small Vessel Disease White Matter Changes) database was analyzed. Out of 256 subjects, 189 participants with a follow-up brain scan were included in the analysis. The linear mixed-effect model was used to compare the 2-year changes in the number of CMBs between men and women.

Results

A total of 65 men and 124 women were analyzed. There were no significant differences in the prevalence (70.8 vs. 71.8%; P = 1.000) and the median [interquartile range (IQR)] number of total CMBs [1 (0-7) vs. 2 (0-7); P = 0.81

SUBMITTER: Yoon CW 

PROVIDER: S-EPMC9810543 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature