Decoding the radiomic features of dorsolateral prefrontal cortex in individuals with accelerated cortical changes: implications for personalized transcranial magnetic stimulation.

ABSTRACT:

Purpose

Image-guided transcranial magnetic stimulation (TMS) is an emerging research field in neuroscience and rehabilitation medicine. Cortical morphometry, as a radiomic phenotype of aging, plays a vital role in developing personalized TMS model, yet few studies are afoot to examine the aging effects on region-specific morphometry and use it in the estimation of TMS-induced electric fields. Our study was aimed to investigate the radiomic features of bilateral dorsolateral prefrontal cortex (DLPFC) and quantify the TMS-induced electric fields during aging.

Approach

Baseline, 1-year and 3-year structural magnetic resonance imaging (MRI) scans from normal aging (NA) adults ( n=32 ) and mild cognitive impairment (MCI) converters ( n=22 ) were drawn from the Open Access Series

SUBMITTER: Lu H 

PROVIDER: S-EPMC9811135 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature