The value of serum IL-4 to predict the survival of MDS patients.

ABSTRACT:

Background

Immune indicators are routinely used for the detection of myelodysplastic syndrome (MDS), but these are not utilized as a reference indicator to assess prognosis in MDS-related prognostic evaluation systems, such as the World Health Organizational prognostic scoring system, the international prostate symptom score, and the revised international prostate symptom score.

Methods

We examined immune indicators, including cluster of differentiation (CD)3, CD4, CD8, CD56, CD19, interleukin (IL)-2, IL-4, IL-6, IL-10, tumor necrosis factor-a, and interferon-γ in 155 newly diagnosed MDS patients. We also conducted a correlation analysis with clinical indices.

Results

IL-4 was found to be a predictor of survival in these 155 patients using the receiver operating chara

SUBMITTER: Liu Z 

PROVIDER: S-EPMC9811803 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature