Inhibition of SARS-CoV2 viral infection with natural antiviral plants constituents: An in-silico approach.

ABSTRACT:

Background and objective

In 2019, a novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) was declared pandemic. Advancement in computational technology has provided rapid and cost-effective techniques to test the efficacy of newer therapeutic agents. This study evaluated some of the potent phytochemicals obtained from AYUSH (Ayurveda, Yoga, Naturopathy, Unani, Siddha, Sowa-Rigpa, and Homeopathy)-listed medicinal plants against SARS-CoV-2 proteins using computational techniques.

Materials and methods

The potential SARS-CoV-2 protein targets were utilized to study the ligand-protein binding characteristics. The bioactive agents were obtained from ashwagandha, liquorice, amla, neem, tinospora, pepper, and stevia. Ivermectin

SUBMITTER: Das K 

PROVIDER: S-EPMC9811905 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature