Functionally gradient three-dimensional graphene foam-based polymeric scaffolds for multilayered tissue regeneration.

ABSTRACT: Physiological bioengineering of multilayered tissues requires an optimized geometric organization with comparable biomechanics. Currently, polymer-reinforced three-dimensional (3D) graphene foams (GFs) are gaining interest in tissue engineering due to their unique morphology, biocompatibility, and similarity to extracellular matrixes. However, the homogeneous reinforcement of single polymers throughout a GF matrix does not provide tissue-level organization. Therefore, a triple-layered structure is developed in a GF matrix to closely mimic native tissue structures of the periodontium of the teeth. The scaffold aims to overcome the issue of layer separation, which generally occurs in multilayered structures due to the poor integration of various layers. The 3D GF matrix was reinforced with a

SUBMITTER: Gupta P 

PROVIDER: S-EPMC9812017 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature